Ohio’s creative scene is a powerhouse of midwestern innovation. Whether you need a branding agency in Columbus, a packaging design firm in Cincinnati, or a full-service digital marketing agency in Ohio, this list covers the best. From Mertz Design Studio and Blackletter to rising stars like Slagle Design and The Karcher Group, these studios deliver high-quality work across disciplines like product design, illustration, web development, and brand storytelling. If you're building a scalable brand or launching a new product, Ohio's top agencies bring both strategy and craft.